Mark L Chiu Selected Research

amivantamab-vmjw

1/2021	Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
1/2017	Fc-mediated activity of EGFR x c-Met bispecific antibody JNJ-61186372 enhanced killing of lung cancer cells.
1/2016	A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

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Mark L Chiu Research Topics

Disease

11	Neoplasms (Cancer) 01/2021 - 03/2011
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 03/2011
2	Insulin Resistance 01/2018 - 01/2017
2	Lung Neoplasms (Lung Cancer) 01/2017 - 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Hematologic Neoplasms (Hematological Malignancy) 12/2019
1	Bites and Stings (Sting) 08/2019
1	Glucose Intolerance 01/2018
1	Hyperinsulinism (Hyperinsulinemia) 01/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2017
1	Hyperglycemia 01/2017
1	Exanthema (Rash) 01/2016
1	Pain (Aches) 05/2013
1	Adenocarcinoma 03/2011
1	Lymphoma (Lymphomas) 03/2011
1	Carcinogenesis 03/2011
1	Neurogenic Inflammation 05/2009

Drug/Important Bio-Agent (IBA)

4	AntibodiesIBA 12/2019 - 12/2016
3	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2017
3	amivantamab-vmjwIBA 01/2021 - 01/2016
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2018 - 12/2016
2	Complement System Proteins (Complement)IBA 01/2020 - 08/2019
2	Bispecific AntibodiesIBA 12/2019 - 08/2019
2	CationsIBA 08/2019 - 05/2009
2	Insulin ReceptorIBA 01/2018 - 01/2017
2	Monoclonal AntibodiesIBA 01/2018 - 01/2017
2	Tyrosine Kinase InhibitorsIBA 01/2017 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 05/2013 - 03/2011
1	Immunoglobulin G (IgG)IBA 01/2020
1	AntigensIBA 01/2020
1	Epithelial Cell Adhesion MoleculeIBA 12/2019
1	blinatumomabIBA 12/2019
1	CytokinesIBA 12/2019
1	2-(N-morpholino)ethanesulfonic acidIBA 08/2019
1	Red Fluorescent ProteinIBA 08/2019
1	Phosphates (Orthophosphate)IBA 08/2019
1	PhycoerythrinIBA 08/2019
1	Bovine Serum AlbuminIBA 08/2019
1	Single-Chain AntibodiesIBA 08/2019
1	Coloring Agents (Dyes)IBA 08/2019
1	Blood Glucose (Blood Sugar)IBA 01/2018
1	Insulin (Novolin)FDA Link 01/2018
1	Glucagon-Like Peptide-1 ReceptorIBA 01/2017
1	Exenatide (Byetta)FDA Link 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	ImmunosorbentsIBA 05/2013
1	Freund's AdjuvantIBA 05/2013
1	EnzymesIBA 05/2013
1	Vincristine (Oncovin)FDA LinkGeneric 03/2011
1	Paclitaxel (Taxol)FDA LinkGeneric 03/2011
1	LigandsIBA 05/2009

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2017
3	Immunotherapy 01/2018 - 12/2016
1	Glycemic Control 01/2018